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The antibody against TRMT2B was raised in rabbit using the Human TRMT2B as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC.
The antibody against TRMT2B was raised in rabbit using the Human TRMT2B as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC.
$600.00
| Cat.No | ADC-46845A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | TRMT2B |
| Target Synonyms | TRMT2B antibody; CXorf34 antibody; tRNA antibody; uracil(54)-C(5))-methyltransferase homolog antibody; EC 2.1.1.35 antibody; TRM2 homolog antibody | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 50% Glycerol, Avoid freeze / thaw cycles., PBS with 0.02% sodium azide | Purification Method | Antigen affinity purified |
| Conjugate | Non-conjugated | Application | ELISA, IHC, WB |
| Storage | Upon receipt |
| Immunogen Description | Human TRMT2B | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q96GJ1 |
Uniprot Id
Q96GJ1
Target Species
Human
Target Name
TRMT2B
Target Full Name
tRNA (uracil-5-)-methyltransferase homolog B
Target Function
Probable S-adenosyl-L-methionine-dependent methyltransferase that catalyzes the formation of 5-methyl-uridine at position 54 (m5U54) in all tRNA. May also have a role in tRNA stabilization or maturation.
Target Protein Families
Class I-like SAM-binding methyltransferase superfamily, RNA M5U methyltransferase family
Target Synonyms
TRMT2B; CXorf34; tRNA; uracil(54)-C(5))-methyltransferase homolog; EC 2.1.1.35; TRM2 homolog
Target Background
This gene encodes a homolog of the TRM2 gene in S. cerevisiae. The yeast gene encodes a tRNA methyltransferase that plays a role in tRNA maturation. The yeast protein also has endo-exonuclease activity and may be involved in DNA double strand break repair. Alternative splicing results in multiple transcripts encoding different isoforms.
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