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Rabbit anti-Human TRMT5 Polyclonal Antibody

The antibody against TRMT5 was raised in rabbit using the Human TRMT5 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB.

ADC-51501A

The antibody against TRMT5 was raised in rabbit using the Human TRMT5 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB.

$600.00

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Specifications


Cat.No ADC-51501A ClonalityPolyclonal
Host SpeciesRabbitTarget NameTRMT5
FormLiquidSpecies ReactivityHuman, Mouse, Rat
IsotypeIgGStorage Buffer50% Glycerol, Avoid freeze / thaw cycles., PBS with 0.1% Sodium Azide
Purification MethodAntigen affinity purifiedConjugateNon-conjugated
ApplicationELISA, WBStorageUpon receipt

Immunogen Information


Immunogen DescriptionHuman TRMT5Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDQ32P41
Background Information
  • Uniprot Id

    Q32P41

  • Target Species

    Human

  • Target Name

    TRMT5

  • Target Full Name

    tRNA (guanine(37)-N(1))-methyltransferase

  • Target Function

    Involved in mitochondrial tRNA methylation. Specifically methylates the N1 position of guanosine-37 in various tRNAs. Methylation is not dependent on the nature of the nucleoside 5' of the target nucleoside. This is the first step in the biosynthesis of wybutosine (yW), a modified base adjacent to the anticodon of tRNAs and required for accurate decoding.

  • Target Involvement

    Combined oxidative phosphorylation deficiency 26 (COXPD26)

  • Target Subcellular Location

    Mitochondrion matrix. Nucleus. Cytoplasm.

  • Target Protein Families

    Class I-like SAM-binding methyltransferase superfamily, TRM5/TYW2 family

  • Target Synonyms

    TRMT5; KIAA1393; TRM5; tRNA; guanine(37)-N1)-methyltransferase; EC 2.1.1.228; M1G-methyltransferase; tRNA [GM37] methyltransferase; tRNA methyltransferase 5 homolog

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