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Rabbit anti-Human TRPV2 Polyclonal Antibody

The antibody against TRPV2 was raised in rabbit using the Recombinant Human Transient receptor potential cation channel subfamily V member 2 protein (1-117AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IHC, IF.

ADC-06197A

The antibody against TRPV2 was raised in rabbit using the Recombinant Human Transient receptor potential cation channel subfamily V member 2 protein (1-117AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IHC, IF.

$299.00

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Specifications


Cat.No ADC-06197A ClonalityPolyclonal
Host SpeciesRabbitTarget NameTRPV2
Target SynonymsTRPV2; VRL; Transient receptor potential cation channel subfamily V member 2; TrpV2; Osm-9-like TRP channel 2; OTRPC2; Vanilloid receptor-like protein 1; VRL-1FormLiquid
Species ReactivityHuman, MouseIsotypeIgG
Storage Buffer0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4Purification Method>95%, Protein G purified
ConjugateNon-conjugatedApplicationELISA, IF, IHC, WB
StorageUpon receipt

Immunogen Information


Immunogen DescriptionRecombinant Human Transient receptor potential cation channel subfamily V member 2 protein (1-117AA)Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDQ9Y5S1
Background Information
  • Uniprot Id

    Q9Y5S1

  • Target Species

    Human

  • Target Name

    TRPV2

  • Target Full Name

    Transient receptor potential cation channel subfamily V member 2

  • Target Function

    Calcium-permeable, non-selective cation channel with an outward rectification. Seems to be regulated, at least in part, by IGF-I, PDGF and neuropeptide head activator. May transduce physical stimuli in mast cells. Activated by temperatures higher than 52 degrees Celsius; is not activated by vanilloids and acidic pH.

  • Target Subcellular Location

    Cell membrane; Multi-pass membrane protein. Cytoplasm. Melanosome.

  • Target Protein Families

    Transient receptor (TC 1.A.4) family, TrpV subfamily, TRPV2 sub-subfamily

  • Target Synonyms

    TRPV2; VRL; Transient receptor potential cation channel subfamily V member 2; TrpV2; Osm-9-like TRP channel 2; OTRPC2; Vanilloid receptor-like protein 1; VRL-1

  • Target Background

    This gene encodes an ion channel that is activated by high temperatures above 52 degrees Celsius. The protein may be involved in transduction of high-temperature heat responses in sensory ganglia. It is thought that in other tissues the channel may be activated by stimuli other than heat.

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