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The antibody against TSHB was raised in rabbit using the Recombinant Human Thyrotropin subunit beta protein (21-132AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA.
The antibody against TSHB was raised in rabbit using the Recombinant Human Thyrotropin subunit beta protein (21-132AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA.
$299.00
| Cat.No | ADC-44107A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | TSHB |
| Target Synonyms | TSHBThyrotropin subunit beta antibody; Thyroid-stimulating hormone subunit beta antibody; TSH-B antibody; TSH-beta antibody; Thyrotropin beta chain antibody; Thyrotropin alfa antibody | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | >95%, Protein G purified |
| Conjugate | Non-conjugated | Application | ELISA |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human Thyrotropin subunit beta protein (21-132AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | P01222 |
Uniprot Id
P01222
Target Species
Human
Target Name
TSHB
Target Full Name
Thyrotropin subunit beta
Target Function
Indispensable for the control of thyroid structure and metabolism.
Target Subcellular Location
Secreted.
Target Protein Families
Glycoprotein hormones subunit beta family
Target Research Area
Signal Transduction
Target Synonyms
TSHBThyrotropin subunit beta; Thyroid-stimulating hormone subunit beta; TSH-B; TSH-beta; Thyrotropin beta chain; Thyrotropin alfa
Target Background
The four human glycoprotein hormones chorionic gonadotropin (CG), luteinizing hormone (LH), follicle stimulating hormone (FSH), and thyroid stimulating hormone (TSH) are dimers consisting of alpha and beta subunits that are associated noncovalently. The alpha subunits of these hormones are identical, however, their beta chains are unique and confer biological specificity. Thyroid stimulating hormone functions in the control of thyroid structure and metabolism. The protein encoded by this gene is the beta subunit of thyroid stimulating hormone. Mutations in this gene are associated with congenital central and secondary hypothyroidism and Hashimoto's thyroiditis. Alternative splicing of this gene results in multiple transcript variants.
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