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The antibody against TTC5 was raised in rabbit using the Recombinant Human Tetratricopeptide repeat protein 5 protein (201-440AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB.
The antibody against TTC5 was raised in rabbit using the Recombinant Human Tetratricopeptide repeat protein 5 protein (201-440AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB.
$299.00
| Cat.No | ADC-19106A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | TTC5 |
| Target Synonyms | TTC5Tetratricopeptide repeat protein 5 antibody; TPR repeat protein 5 antibody; Stress-responsive activator of p300 antibody; Strap antibody | Form | Liquid |
| Species Reactivity | Human, Mouse | Isotype | IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | >95%, Protein G purified |
| Conjugate | Non-conjugated | Application | ELISA, WB |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human Tetratricopeptide repeat protein 5 protein (201-440AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q8N0Z6 |
Uniprot Id
Q8N0Z6
Target Species
Human
Target Name
TTC5
Target Full Name
Tetratricopeptide repeat protein 5
Target Function
Adapter protein involved in p53/TP53 response that acts by regulating and mediating the assembly of multi-protein complexes. Required to facilitate the interaction between JMY and p300/EP300 and increase p53/TP53-dependent transcription and apoptosis. Prevents p53/TP53 degradation by MDM2.
Target Subcellular Location
Nucleus. Cytoplasm.
Target Synonyms
TTC5Tetratricopeptide repeat protein 5; TPR repeat protein 5; Stress-responsive activator of p300; Strap
Target Background
Predicted to enable DNA binding activity and chromatin binding activity. Predicted to be involved in DNA repair. Predicted to act upstream of or within positive regulation of transcription by RNA polymerase II. Located in nucleoplasm.
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