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Rabbit anti-Human TULP1 Polyclonal Antibody

The antibody against TULP1 was raised in rabbit using the Human TULP1 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC, IF.

ADC-46820A

The antibody against TULP1 was raised in rabbit using the Human TULP1 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC, IF.

$600.00

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Specifications


Cat.No ADC-46820A ClonalityPolyclonal
Host SpeciesRabbitTarget NameTULP1
FormLiquidSpecies ReactivityHuman, Mouse, Rat
IsotypeIgGStorage Buffer50% Glycerol, Avoid freeze / thaw cycles., PBS with 0.02% sodium azide
Purification MethodAntigen affinity purifiedConjugateNon-conjugated
ApplicationELISA, IF, IHC, WBStorageUpon receipt

Immunogen Information


Immunogen DescriptionHuman TULP1Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDO00294
Background Information
  • Uniprot Id

    O00294

  • Target Species

    Human

  • Target Name

    TULP1

  • Target Full Name

    Tubby-related protein 1

  • Target Function

    Required for normal development of photoreceptor synapses. Required for normal photoreceptor function and for long-term survival of photoreceptor cells. Interacts with cytoskeleton proteins and may play a role in protein transport in photoreceptor cells. Binds lipids, especially phosphatidylinositol 3-phosphate, phosphatidylinositol 4-phosphate, phosphatidylinositol 5-phosphate, phosphatidylinositol 3,4-bisphosphate, phosphatidylinositol 4,5-bisphosphate, phosphatidylinositol 3,4,5-bisphosphate, phosphatidylserine and phosphatidic acid (in vitro). Contribute to stimulation of phagocytosis of apoptotic retinal pigment epithelium (RPE) cells and macrophages.

  • Target Involvement

    Retinitis pigmentosa 14 (RP14); Leber congenital amaurosis 15 (LCA15)

  • Target Subcellular Location

    Cytoplasm. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Secreted. Cell junction, synapse.

  • Target Protein Families

    TUB family

  • Target Tissue Specificity

    Retina-specific.

  • Target Synonyms

    RP14; Tubby like protein 1; Tubby related protein 1 (Tubby like protein 1); Tubby related protein 1; Tubby-like protein 1; Tubby-related protein 1; TUBL1; TULP 1; Tulp1; TULP1_HUMAN

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