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The antibody against USP6NL was raised in rabbit using the Recombinant Human USP6 N-terminal-like protein (387-693AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.
The antibody against USP6NL was raised in rabbit using the Recombinant Human USP6 N-terminal-like protein (387-693AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.
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Immunohistochemistry of paraffin-embedded human small intestine tissue using USP6NL Antibody at dilution of 1:100
Immunohistochemistry of paraffin-embedded human adrenal gland tissue using USP6NL Antibody at dilution of 1:1002
| Cat.No | ADC-10209A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | USP6NL |
| Form | Liquid | Species Reactivity | Human |
| Isotype | IgG | Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 |
| Purification Method | >95%, Protein G purified | Conjugate | Non-conjugated |
| Application | ELISA, IHC | Storage | Upon receipt |
| Immunogen Description | Recombinant Human USP6 N-terminal-like protein (387-693AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q92738 |
Uniprot Id
Q92738
Target Species
Human
Target Name
USP6NL
Target Full Name
USP6 N-terminal-like protein
Target Function
Acts as a GTPase-activating protein for RAB5A and RAB43. Involved in receptor trafficking. In complex with EPS8 inhibits internalization of EGFR. Involved in retrograde transport from the endocytic pathway to the Golgi apparatus. Involved in the transport of Shiga toxin from early and recycling endosomes to the trans-Golgi network. Required for structural integrity of the Golgi complex.
Target Subcellular Location
Golgi apparatus. Cytoplasmic vesicle.
Target Tissue Specificity
Widely expressed.
Target Synonyms
KIAA0019; Related to the N terminus of tre; Related to the N-terminus of tre; RN tre; RN-tre; RNTRE; TRE2NL; US6NL_HUMAN; USP6 N terminal like; USP6 N terminal like protein; USP6 N-terminal-like protein; USP6NL
Target Background
Enables GTPase activator activity and small GTPase binding activity. Involved in several processes, including plasma membrane to endosome transport; positive regulation of GTPase activity; and retrograde transport, plasma membrane to Golgi. Located in cytoplasmic vesicle and plasma membrane.
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