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The antibody against UTY was raised in rabbit using the Recombinant Human Histone demethylase UTY protein (1-72AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IF.
The antibody against UTY was raised in rabbit using the Recombinant Human Histone demethylase UTY protein (1-72AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IF.
$299.00
| Cat.No | ADC-06737A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | UTY |
| Form | Liquid | Species Reactivity | Human |
| Isotype | IgG | Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 |
| Purification Method | >95%, Protein G purified | Conjugate | Non-conjugated |
| Application | ELISA, IF | Storage | Upon receipt |
| Immunogen Description | Recombinant Human Histone demethylase UTY protein (1-72AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | O14607 |
Uniprot Id
O14607
Target Species
Human
Target Name
UTY
Target Full Name
Histone demethylase UTY
Target Function
Male-specific histone demethylase that catalyzes trimethylated 'Lys-27' (H3K27me3) demethylation in histone H3. Has relatively low lysine demethylase activity.
Target Subcellular Location
Nucleus.
Target Protein Families
UTX family
Target Synonyms
Histone demethylase UTY; Ubiquitously transcribed TPR protein on the Y chromosome; Ubiquitously transcribed Y chromosome tetratricopeptide repeat protein; Ubiquitously-transcribed TPR protein on the Y chromosome; Ubiquitously-transcribed Y chromosome tetratricopeptide repeat protein; UTY; UTY_HUMAN
Target Background
This gene encodes a protein containing tetratricopeptide repeats which are thought to be involved in protein-protein interactions. The encoded protein is also a minor histocompatibility antigen which may induce graft rejection of male stem cell grafts. A large number of alternatively spliced transcripts have been observed for this gene, but the full length nature of some of these variants has not been determined.
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