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The antibody against VKORC1 was raised in rabbit using the Recombinant Human Vitamin K epoxide reductase complex subunit 1 protein (30-74AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.
The antibody against VKORC1 was raised in rabbit using the Recombinant Human Vitamin K epoxide reductase complex subunit 1 protein (30-74AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.
$299.00
| Cat.No | ADC-04948A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | VKORC1 |
| Target Synonyms | 3-epoxide reductase subunit 1 antibody; Vitamin K1 epoxide reductase (warfarin sensitive) antibody; VKCFD2 antibody; VKOR antibody; VKOR1_HUMAN antibody; VKORC1 antibody | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | >95%, Protein G purified |
| Conjugate | Non-conjugated | Application | ELISA, IHC |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human Vitamin K epoxide reductase complex subunit 1 protein (30-74AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q9BQB6 |
Uniprot Id
Q9BQB6
Target Species
Human
Target Name
VKORC1
Target Full Name
Vitamin K epoxide reductase complex subunit 1
Target Function
Involved in vitamin K metabolism. Catalytic subunit of the vitamin K epoxide reductase (VKOR) complex which reduces inactive vitamin K 2,3-epoxide to active vitamin K. Vitamin K is required for the gamma-carboxylation of various proteins, including clotting factors, and is required for normal blood coagulation, but also for normal bone development.
Target Involvement
Combined deficiency of vitamin K-dependent clotting factors 2 (VKCFD2); Coumarin resistance (CMRES)
Target Subcellular Location
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Target Protein Families
VKOR family
Target Tissue Specificity
Expressed at highest levels in fetal and adult liver, followed by fetal heart, kidney, and lung, adult heart, and pancreas.
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