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The antibody against WARS2 was raised in rabbit using the Human WARS2 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB.
The antibody against WARS2 was raised in rabbit using the Human WARS2 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB.
$600.00
| Cat.No | ADC-46712A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | WARS2 |
| Target Synonyms | WARS2 antibody; Tryptophan--tRNA ligase antibody; mitochondrial antibody; EC 6.1.1.2; antibody; Mt)TrpRS antibody; Tryptophanyl-tRNA synthetase antibody; TrpRS antibody | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, Avoid freeze / thaw cycles., PBS with 0.1% Sodium Azide | Purification Method | Antigen affinity purified |
| Conjugate | Non-conjugated | Application | ELISA, WB |
| Storage | Upon receipt |
| Immunogen Description | Human WARS2 | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q9UGM6 |
Uniprot Id
Q9UGM6
Target Species
Human
Target Name
WARS2
Target Full Name
Tryptophan--tRNA ligase, mitochondrial
Target Function
Mitochondrial aminoacyl-tRNA synthetase that activate and transfer the amino acids to their corresponding tRNAs during the translation of mitochondrial genes and protein synthesis.
Target Involvement
Neurodevelopmental disorder, mitochondrial, with abnormal movements and lactic acidosis, with or without seizures (NEMMLAS)
Target Subcellular Location
Mitochondrion matrix.
Target Protein Families
Class-I aminoacyl-tRNA synthetase family
Target Tissue Specificity
Brain.
Target Synonyms
WARS2; Tryptophan--tRNA ligase; mitochondrial; EC 6.1.1.2;; Mt)TrpRS; Tryptophanyl-tRNA synthetase; TrpRS
Target Background
Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAs, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. Two forms of tryptophanyl-tRNA synthetase exist, a cytoplasmic form, named WARS, and a mitochondrial form, named WARS2. This gene encodes the mitochondrial tryptophanyl-tRNA synthetase. Two alternative transcripts encoding different isoforms have been described.
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