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Rabbit anti-Human WFDC1 Polyclonal Antibody

The antibody against WFDC1 was raised in rabbit using the Synthetic peptide of Human WFDC1 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC.

ADC-25503A

The antibody against WFDC1 was raised in rabbit using the Synthetic peptide of Human WFDC1 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC.

$299.00

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Specifications


Cat.No ADC-25503A ClonalityPolyclonal
Host SpeciesRabbitTarget NameWFDC1
FormLiquidSpecies ReactivityHuman, Mouse
IsotypeIgGStorage Buffer0.05% NaN3, 40% Glycerol., pH7.4 PBS
Purification MethodAntigen affinity purifiedConjugateNon-conjugated
ApplicationELISA, IHCStorageUpon receipt

Immunogen Information


Immunogen DescriptionSynthetic peptide of Human WFDC1Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDQ9HC57
Background Information
  • Uniprot Id

    Q9HC57

  • Target Species

    Human

  • Target Name

    WFDC1

  • Target Full Name

    WAP four-disulfide core domain protein 1

  • Target Function

    Has growth inhibitory activity.

  • Target Subcellular Location

    Secreted.

  • Target Synonyms

    Prostate stromal protein ps20; PS20; ps20 growth inhibitor; WAP four disulfide core domain 1; WAP four disulfide core domain 1 homolog; WAP four-disulfide core domain protein 1; Wfdc1; WFDC1_HUMAN

  • Target Background

    This gene encodes a member of the WAP-type four disulfide core domain family. The WAP-type four-disulfide core domain contains eight cysteines forming four disulfide bonds at the core of the protein, and functions as a protease inhibitor in many family members. This gene is mapped to chromosome 16q24, an area of frequent loss of heterozygosity in cancers, including prostate, breast and hepatocellular cancers and Wilms' tumor. This gene is downregulated in many cancer types and may be involved in the inhibition of cell proliferation. The encoded protein may also play a role in the susceptibility of certain CD4 memory T cells to human immunodeficiency virus infection. Alternative splicing results in multiple transcript variants.

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