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Rabbit anti-Human WNT2B Polyclonal Antibody

The antibody against WNT2B was raised in rabbit using the Synthetic peptide of Human WNT2B as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC.

ADC-25467A

The antibody against WNT2B was raised in rabbit using the Synthetic peptide of Human WNT2B as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC.

$299.00

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Specifications


Cat.No ADC-25467A ClonalityPolyclonal
Host SpeciesRabbitTarget NameWNT2B
FormLiquidSpecies ReactivityHuman, Mouse
IsotypeIgGStorage Buffer0.05% NaN3, 40% Glycerol., pH7.4 PBS
Purification MethodAntigen affinity purifiedConjugateNon-conjugated
ApplicationELISA, IHCStorageUpon receipt

Immunogen Information


Immunogen DescriptionSynthetic peptide of Human WNT2BTarget SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDQ93097
Background Information
  • Uniprot Id

    Q93097

  • Target Species

    Human

  • Target Name

    WNT2B

  • Target Full Name

    Protein Wnt-2b

  • Target Function

    Ligand for members of the frizzled family of seven transmembrane receptors. Functions in the canonical Wnt/beta-catenin signaling pathway. Plays a redundant role in embryonic lung development.

  • Target Subcellular Location

    Secreted, extracellular space, extracellular matrix. Secreted.

  • Target Protein Families

    Wnt family

  • Target Tissue Specificity

    Isoform 1 is expressed in adult heart, brain, placenta, lung, prostate, testis, ovary, small intestine and colon. In the adult brain, it is mainly found in the caudate nucleus, subthalamic nucleus and thalamus. Also detected in fetal brain, lung and kidne

  • Target Research Area

    Cancer

  • Target Synonyms

    WNT2B; WNT13; Protein Wnt-2b; Protein Wnt-13

  • Target Background

    This gene encodes a member of the wingless-type MMTV integration site (WNT) family of highly conserved, secreted signaling factors. WNT family members function in a variety of developmental processes including regulation of cell growth and differentiation and are characterized by a WNT-core domain. This gene may play a role in human development as well as carcinogenesis. Alternative splicing results in multiple transcript variants.

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