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The antibody against XKR8 was raised in rabbit using the Recombinant Human XK-related protein 8 protein (69-158AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IHC, IF.
The antibody against XKR8 was raised in rabbit using the Recombinant Human XK-related protein 8 protein (69-158AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IHC, IF.
$299.00
| Cat.No | ADC-14981A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | XKR8 |
| Form | Liquid | Species Reactivity | Human |
| Isotype | IgG | Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 |
| Purification Method | >95%, Protein G purified | Conjugate | Non-conjugated |
| Application | ELISA, IF, IHC, WB | Storage | Upon receipt |
| Immunogen Description | Recombinant Human XK-related protein 8 protein (69-158AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q9H6D3 |
Uniprot Id
Q9H6D3
Target Species
Human
Target Name
XKR8
Target Full Name
XK-related protein 8
Target Function
Phospholipid scramblase that promotes phosphatidylserine exposure on apoptotic cell surface. Phosphatidylserine is a specific marker only present at the surface of apoptotic cells and acts as a specific signal for engulfment. Required for the clearance of apoptotic cells, such as engulfment of apoptotic germ cells by Sertoli cells, clearance of senescent neutrophils or regulation of bipolar cell numbers in the retina. Has no effect on calcium-induced exposure of phosphatidylserine. Promotes myoblast differentiation and survival.; (Microbial infection) Incorporated into Ebola virus-like particles, where its phospholipid scramblase activity is required to promote phosphatidylserine exposure on the surface of viral particles. Externalization of phosphatidylserine on the surface of viral particles is required for uptake by host cells.
Target Subcellular Location
Cell membrane; Multi-pass membrane protein. Cytoplasm, perinuclear region.
Target Protein Families
XK family
Target Synonyms
FLJ10307; hXkr8; RP11-460I13.3; X Kell blood group precursor-related family; member 8; XK-related protein 8; XKR8; XKR8_HUMAN; XRG8
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