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The antibody against ZFP57 was raised in rabbit using the Recombinant Human Zinc finger protein 57 homolog protein (183-295AA) as the immunogen. This antibody exists as a fitc conjugated isotype IgG, purified by protein G with a purity greater than 95%.
The antibody against ZFP57 was raised in rabbit using the Recombinant Human Zinc finger protein 57 homolog protein (183-295AA) as the immunogen. This antibody exists as a fitc conjugated isotype IgG, purified by protein G with a purity greater than 95%.
$299.00
| Cat.No | ADC-03837A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | ZFP57 |
| Target Synonyms | ZFP57 antibody; C6orf40 antibody; ZNF698 antibody; Zinc finger protein 57 homolog antibody; Zfp-57 antibody; Zinc finger protein 698 antibody | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | >95%, Protein G purified |
| Conjugate | FITC conjugated | Storage | Upon receipt |
| Immunogen Description | Recombinant Human Zinc finger protein 57 homolog protein (183-295AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q9NU63 |
Uniprot Id
Q9NU63
Target Species
Human
Target Name
ZFP57
Target Full Name
Zinc finger protein 57 homolog
Target Function
Transcription regulator required to maintain maternal and paternal gene imprinting, a process by which gene expression is restricted in a parent of origin-specific manner by epigenetic modification of genomic DNA and chromatin, including DNA methylation. Acts by controlling DNA methylation during the earliest multicellular stages of development at multiple imprinting control regions (ICRs). Acts together with ZNF445, but ZNF445 seems to be the major factor in human early embryonic imprinting maintenance. In contrast, in mice, ZFP57 plays the predominant role in imprinting maintenance. Required for the establishment of maternal methylation imprints at SNRPN locus. Acts as a transcriptional repressor in Schwann cells. Binds to a 5'-TGCCGC-3' consensus sequence and recognizes the methylated CpG within this element.
Target Involvement
Transient neonatal diabetes mellitus 1 (TNDM1)
Target Subcellular Location
Nucleus.
Target Protein Families
Krueppel C2H2-type zinc-finger protein family, ZFP57 subfamily
Target Synonyms
ZFP57; C6orf40; ZNF698; Zinc finger protein 57 homolog; Zfp-57; Zinc finger protein 698
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