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The antibody against ZFYVE26 was raised in rabbit using the Recombinant Human Zinc finger FYVE domain-containing protein 26 protein (2306-2473AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC, IF.
The antibody against ZFYVE26 was raised in rabbit using the Recombinant Human Zinc finger FYVE domain-containing protein 26 protein (2306-2473AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC, IF.
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Immunohistochemistry of paraffin-embedded human brain tissue using ZFYVE26 Antibody at dilution of 1:100
Immunofluorescent analysis of HepG2 cells using ZFYVE26 Antibody at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)2
| Cat.No | ADC-09842A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | ZFYVE26 |
| Form | Liquid | Species Reactivity | Human |
| Isotype | IgG | Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 |
| Purification Method | >95%, Protein G purified | Conjugate | Non-conjugated |
| Application | ELISA, IF, IHC | Storage | Upon receipt |
| Immunogen Description | Recombinant Human Zinc finger FYVE domain-containing protein 26 protein (2306-2473AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q68DK2 |
Uniprot Id
Q68DK2
Target Species
Human
Target Name
ZFYVE26
Target Full Name
Zinc finger FYVE domain-containing protein 26
Target Function
Phosphatidylinositol 3-phosphate-binding protein required for the abcission step in cytokinesis: recruited to the midbody during cytokinesis and acts as a regulator of abcission. May also be required for efficient homologous recombination DNA double-strand break repair.
Target Involvement
Spastic paraplegia 15, autosomal recessive (SPG15)
Target Subcellular Location
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Midbody. Note=Localizes to the centrosome during all stages of the cell cycle. Recruited to the midbody during cytokinesis by KIF13A.
Target Tissue Specificity
Strongest expression in the adrenal gland, bone marrow, adult brain, fetal brain, lung, placenta, prostate, skeletal muscle, testis, thymus, and retina. Intermediate levels are detected in other structures, including the spinal cord.
Target Synonyms
DKFZp686F19106; DKFZp781H1112; FYVE domain-containing centrosomal protein; FYVE-CENT; KIAA0321; Spastic paraplegia 15 (complicated autosomal recessive); Spastizin; SPG15; ZFY26_HUMAN; ZFYVE 26; ZFYVE26; Zinc finger FYVE domain containing 26; Zinc finger FYVE domain containing protein 26; Zinc finger FYVE domain-containing protein 26
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