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The antibody against ZHX2 was raised in rabbit using the Synthesized peptide derived from the C-terminal region of Human ZHX2. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on IHC, ELISA.
The antibody against ZHX2 was raised in rabbit using the Synthesized peptide derived from the C-terminal region of Human ZHX2. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on IHC, ELISA.
$167.00
| Cat.No | ADC-35872A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | ZHX2 |
| Form | Liquid | Species Reactivity | Human, Mouse |
| Isotype | IgG | Storage Buffer | 0.5% BSA and 0.02% sodium azide., Liquid in PBS containing 50% glycerol |
| Purification Method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. | Conjugate | Non-conjugated |
| Application | ELISA, IHC | Storage | Upon receipt |
| Immunogen Description | Synthesized peptide derived from the C-terminal region of Human ZHX2. | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q9Y6X8 |
Uniprot Id
Q9Y6X8
Target Species
Human
Target Name
ZHX2
Target Full Name
Zinc fingers and homeoboxes protein 2
Target Function
Acts as a transcriptional repressor. Represses the promoter activity of the CDC25C gene stimulated by NFYA. May play a role in retinal development where it regulates the composition of bipolar cell populations, by promoting differentiation of bipolar OFF-type cells. In the brain, may promote maintenance and suppress differentiation of neural progenitor cells in the developing cortex.
Target Subcellular Location
Nucleus.
Target Protein Families
ZHX family
Target Tissue Specificity
Ubiquitously expressed. Expressed in podocytes.
Target Synonyms
AFP regulator 1; AFR1; Alpha fetoprotein regulator 1; Alpha-fetoprotein regulator 1; KIAA0854; RAF; Regulator of AFP; Transcription factor ZHX2; ZHX2; ZHX2_HUMAN; Zinc finger and homeodomain protein 2; Zinc fingers and homeoboxes 2; Zinc fingers and homeoboxes protein 2
Target Background
The members of the zinc fingers and homeoboxes gene family are nuclear homodimeric transcriptional repressors that interact with the A subunit of nuclear factor-Y (NF-YA) and contain two C2H2-type zinc fingers and five homeobox DNA-binding domains. This gene encodes member 2 of this gene family. In addition to forming homodimers, this protein heterodimerizes with member 1 of the zinc fingers and homeoboxes family.
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