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Rabbit anti-Mus musculus (Mouse) Adh7 Polyclonal Antibody

The antibody against Adh7 was raised in rabbit using the Recombinant Mouse Alcohol dehydrogenase class 4 mu/sigma chain protein (1-374AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB.

ADC-19943A

The antibody against Adh7 was raised in rabbit using the Recombinant Mouse Alcohol dehydrogenase class 4 mu/sigma chain protein (1-374AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB.

$299.00

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Specifications


Cat.No ADC-19943A ClonalityPolyclonal
Host SpeciesRabbitTarget NameAdh7
FormLiquidSpecies ReactivityMouse
IsotypeIgGStorage Buffer0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4
Purification Method>95%, Protein G purifiedConjugateNon-conjugated
ApplicationELISA, WBStorageUpon receipt

Immunogen Information


Immunogen DescriptionRecombinant Mouse Alcohol dehydrogenase class 4 mu/sigma chain protein (1-374AA)Target SpeciesMus musculus (Mouse)
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDQ64437
Background Information
  • Uniprot Id

    Q64437

  • Target Species

    Mouse

  • Target Name

    ADH7

  • Target Full Name

    All-trans-retinol dehydrogenase [NAD(+)] ADH7

  • Target Function

    Catalyzes the NAD-dependent oxidation of all-trans-retinol, alcohol, aldehyde and omega-hydroxy fatty acids and their derivatives. Oxidizes preferentially all trans-retinol, all-trans-4-hydroxyretinol, 9-cis-retinol, 2-hexenol, and long chain omega-hydroxy fatty acids such as juniperic acid. In vitro can also catalyzes the NADH-dependent reduction of all-trans-retinal and aldehydes and their derivatives. Reduces preferentially all trans-retinal, all-trans-4-oxoretinal and hexanal. Catalyzes in the oxidative direction with higher efficiency. Therefore may participate in retinoid metabolism, fatty acid omega-oxidation, and elimination of cytotoxic aldehydes produced by lipid peroxidation.

  • Target Subcellular Location

    Cytoplasm.

  • Target Protein Families

    Zinc-containing alcohol dehydrogenase family, Class-IV subfamily

  • Target Tissue Specificity

    High expression in the stomach mucosa. Lower expression in eye, thymus, skin and ovary. Very low expression in small intestine, liver and uterus.

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