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Rabbit anti-Mycobacterium tuberculosis lprG Polyclonal Antibody

The antibody against lprG was raised in rabbit using the Recombinant Mycobacterium tuberculosis lprG protein (27-236aa ) as the immunogen. This antibody exists as a non-conjugated isotype IgG, Protein G Purified. This antibody has been validated on ELISA, WB.

ADC-54703A

The antibody against lprG was raised in rabbit using the Recombinant Mycobacterium tuberculosis lprG protein (27-236aa ) as the immunogen. This antibody exists as a non-conjugated isotype IgG, Protein G Purified. This antibody has been validated on ELISA, WB.

$299.00

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Specifications


Cat.No ADC-54703A ClonalityPolyclonal
Host SpeciesRabbitTarget NamelprG
Target SynonymsLipoarabinomannan carrier protein LprG (27 kDa lipoprotein) (Antigen P27) (Lipoprotein LprG) (Triacylglyceride transfer protein LprG), lpp-27, lprGFormLiquid
Species ReactivityMycobacterium tuberculosisIsotypeIgG
Storage Buffer0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4Purification MethodProtein G purified
ConjugateNon-conjugatedApplicationELISA, WB
StorageUpon receipt

Immunogen Information


Immunogen DescriptionRecombinant Mycobacterium tuberculosis lprG protein (27-236aa )Target SpeciesMycobacterium tuberculosis
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDP9WK44
Background Information
  • Uniprot Id

    P9WK44

  • Target Species

    Mycobacterium tuberculosis

  • Target Name

    LPRG

  • Target Function

    Probably helps membrane protein MT1454 (P55) transport triacylglycerides (TAG) across the inner cell membrane into the periplasm and probably ultimately to the outer membrane. TAG probably regulates lipid metabolism and growth regulation. Binds di- and triacylated phosphatidyl-myo-inositol mannosides (PIMs), and glycolipid lipoglycan modulins lipoarabinomannan (LAM) and lipomannan (LM), facilitating their recognition by TLR2. Required for activity of drug efflux transporter MT1454. Required, probably with MT1454, for normal surface localization of LAM.; Constitutes a host TLR2 agonist (toll-like receptor).

  • Target Subcellular Location

    Cell inner membrane; Lipid-anchor. Secreted, cell wall. Secreted.

  • Target Protein Families

    LppX/LprAFG lipoprotein family

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