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The antibody against G was raised in rabbit using the Recombinant Rabies virus Glycoprotein protein (20-459AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB.
The antibody against G was raised in rabbit using the Recombinant Rabies virus Glycoprotein protein (20-459AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB.
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Western blotAll lanes: Rabies virus Glycoprotein (G) antibody at 1: 500Lane 1: Rabies virus antigen 1: 2Lane 2: Rabies virus antigen 1: 10Lane 3: Rabies virus antigen 1: 20SecondaryGoat polyclonal to rabbit IgG at 1/10000 dilutionPredicted band size: 55 kDaObserved band size: 55 kDa
| Cat.No | ADC-46109A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | G |
| Target Synonyms | GGlycoprotein antibody | Form | Liquid |
| Species Reactivity | Rabies virus | Isotype | IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | >95%, Protein G purified |
| Conjugate | Non-conjugated | Application | ELISA, WB |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Rabies virus Glycoprotein protein (20-459AA) | Target Species | Rabies virus |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | P03524 |
Uniprot Id
P03524
Target Species
Rabies virus
Target Name
G
Target Function
Attaches the virus to host cellular receptor, inducing endocytosis of the virion. In the endosome, the acidic pH induces conformational changes in the glycoprotein trimer, which trigger fusion between virus and cell membrane. There is convincing in vitro evidence that the muscular form of the nicotinic acetylcholine receptor (nAChR), the neuronal cell adhesion molecule (NCAM), and the p75 neurotrophin receptor (p75NTR) bind glycoprotein and thereby facilitate rabies virus entry into cells.
Target Subcellular Location
Virion membrane; Single-pass type I membrane protein.
Target Protein Families
Lyssavirus glycoprotein family
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