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Rabbit anti-Scytonema varium Scytovirin Polyclonal Antibody, FITC conjugated

The antibody against Scytovirin was raised in rabbit using the Recombinant Scytonema varium Scytovirin protein (1-95AA) as the immunogen. This antibody exists as a fitc conjugated isotype IgG, purified by protein G with a purity greater than 95%.

ADC-20723A

The antibody against Scytovirin was raised in rabbit using the Recombinant Scytonema varium Scytovirin protein (1-95AA) as the immunogen. This antibody exists as a fitc conjugated isotype IgG, purified by protein G with a purity greater than 95%.

$299.00

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Specifications


Cat.No ADC-20723A ClonalityPolyclonal
Host SpeciesRabbitTarget NameScytovirin
Target SynonymsScytovirin antibody; SVN antibodyFormLiquid
Species ReactivityScytonema variumIsotypeIgG
Storage Buffer0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4Purification Method>95%, Protein G purified
ConjugateFITC conjugatedStorageUpon receipt

Immunogen Information


Immunogen DescriptionRecombinant Scytonema varium Scytovirin protein (1-95AA)Target SpeciesScytonema varium
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDP86041
Background Information
  • Uniprot Id

    P86041

  • Target Species

    Scytonema varium

  • Target Function

    Has strong anti-HIV activity against T-tropic strains of HIV-1 and weaker activity against M-tropic strains of HIV-1. Inhibits HIV-1 fusion and infection of CD4 LTR beta-gal cells in vitro. Inhibits fusion of HIV infected CEM-SS cells with uninfected CEM-SS cells, and fusion of HIV-1 Env expressing HL2/3 cells with CD4 LTR beta-gal cells. Binds to HIV gp120, HIV gp160 and to a lesser extent HIV gp41. Binding to HIV gp120 is glycosylation dependent. Binds with high specificity to the tetrasaccharide Man-alpha-1,2-Man-alpha-1,6-Man-alpha-1,6-Man and also binds the higher-order oligosaccharides oligomannose 8 and oligomannose 9. Does not bind to monosaccharides, complex or hybrid N-linked oligosaccharides or chitin.

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