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The antibody against scn was raised in rabbit using the Recombinant Staphylococcus aureus Staphylococcal complement inhibitor protein (32-116AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA.
The antibody against scn was raised in rabbit using the Recombinant Staphylococcus aureus Staphylococcal complement inhibitor protein (32-116AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA.
$299.00
| Cat.No | ADC-18503A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | scn |
| Target Synonyms | scn antibody; SA1754 antibody; Staphylococcal complement inhibitor antibody; SCIN antibody | Form | Liquid |
| Species Reactivity | Staphylococcus aureus | Isotype | IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | >95%, Protein G purified |
| Conjugate | Non-conjugated | Application | ELISA |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Staphylococcus aureus Staphylococcal complement inhibitor protein (32-116AA) | Target Species | Staphylococcus aureus (strain N315) |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q99SU9 |
Uniprot Id
Q99SU9
Target Species
Staphylococcus aureus
Target Name
SCN
Target Function
Involved in countering the first line of host defense mechanisms. Efficiently inhibits opsonization, phagocytosis and killing of S.aureus by human neutrophils. Acts by binding and stabilizing human C3 convertases (C4b2a and C3bBb), leading to their inactivation. The convertases are no longer able to cleave complement C3, therefore preventing further C3b deposition on the bacterial surface and phagocytosis of the bacterium. Also prevents C5a-induced neutrophil responses.
Target Subcellular Location
Secreted.
Target Protein Families
SCIN family
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