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The antibody against cas3 was raised in rabbit using the Recombinant Thermus thermophilus CRISPR-associated endonuclease/helicase Cas3 protein (120-226AA) as the immunogen. This antibody exists as a biotin conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA.
The antibody against cas3 was raised in rabbit using the Recombinant Thermus thermophilus CRISPR-associated endonuclease/helicase Cas3 protein (120-226AA) as the immunogen. This antibody exists as a biotin conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA.
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| Cat.No | ADC-02671A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | cas3 |
| Target Synonyms | cas3 antibody; TTHB187CRISPR-associated endonuclease/helicase Cas3 antibody; EC 3.1.-.- antibody; EC 3.6.4.- antibody; CRISPR-associated ssDNA endonuclease/helicase Cas3 antibody | Form | Liquid |
| Species Reactivity | Thermus thermophilus | Isotype | IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | >95%, Protein G purified |
| Conjugate | Biotin conjugated | Application | ELISA |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Thermus thermophilus CRISPR-associated endonuclease/helicase Cas3 protein (120-226AA) | Target Species | Thermus thermophilus |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q53VY2 |
Uniprot Id
Q53VY2
Target Species
Thermus thermophilus
Target Name
CAS3
Target Function
CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Cas3 plus Cascade participate in CRISPR interference, the third stage of CRISPR immunity. The N-terminal domain (residues 6-260) acts as a ssDNA endonuclease, has no activity on dsDNA.
Target Protein Families
CRISPR-associated nuclease Cas3-HD family; CRISPR-associated helicase Cas3 family
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