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The antibody against PNKD was raised in rabbit using the Recombinant Human Probable hydrolase PNKD protein (78-243AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB.
The antibody against PNKD was raised in rabbit using the Recombinant Human Probable hydrolase PNKD protein (78-243AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB.
$299.00
| Cat.No | ADC-13283A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | PNKD |
| Form | Liquid | Species Reactivity | Human, Mouse |
| Isotype | IgG | Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 |
| Purification Method | >95%, Protein G purified | Conjugate | Non-conjugated |
| Application | ELISA, WB | Storage | Upon receipt |
| Immunogen Description | Recombinant Human Probable hydrolase PNKD protein (78-243AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q8N490 |
Uniprot Id
Q8N490
Target Species
Human
Target Name
PNKD
Target Full Name
Probable hydrolase PNKD
Target Function
Probable hydrolase that plays an aggravative role in the development of cardiac hypertrophy via activation of the NF-kappa-B signaling pathway.
Target Involvement
Dystonia 8 (DYT8)
Target Subcellular Location
[Isoform 1]: Membrane; Peripheral membrane protein.; [Isoform 2]: Cytoplasm. Nucleus.; [Isoform 3]: Mitochondrion.
Target Protein Families
Metallo-beta-lactamase superfamily, Glyoxalase II family
Target Tissue Specificity
Isoform 1 is only expressed in the brain. Isoform 2 is ubiquitously detected with highest expression in skeletal muscle and detected in myocardial myofibrils. Variant Val-7 and Val-9 are detected in the brain only.
Target Synonyms
2210013N15Rik; 2810403H05Rik; AI854243; BRAIN PROTEIN 17; BRP17; DYT8; FKSG19; FPD1; KIAA1184; KIPP1184; MNCb-5687; MR-1; MR1; Myofibrillogenesis regulator 1; Paroxysmal nonkinesiogenic dyskinesia protein; PDC; PKND1; Pnkd; PNKD_HUMAN; Probable hydrolase PNKD; TAHCCP2; Trans-activated by hepatitis C virus core protein 2
Target Background
This gene is thought to play a role in the regulation of myofibrillogenesis. Mutations in this gene have been associated with the movement disorder paroxysmal non-kinesigenic dyskinesia. Alternative splicing results in multiple transcript variants.
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