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The antibody against FEZ1 was raised in rabbit using the Recombinant Human Fasciculation and elongation protein zeta-1 protein (12-200AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC, IF.
The antibody against FEZ1 was raised in rabbit using the Recombinant Human Fasciculation and elongation protein zeta-1 protein (12-200AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC, IF.
$299.00
Immunohistochemistry of paraffin-embedded human brain tissue using FEZ1 Antibody at dilution of 1:100
Immunofluorescent analysis of HepG2 cells using FEZ1 Antibody at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)2
| Cat.No | ADC-13418A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | FEZ1 |
| Target Synonyms | FEZ1Fasciculation and elongation protein zeta-1 antibody; Zygin I antibody; Zygin-1 antibody | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | >95%, Protein G purified |
| Conjugate | Non-conjugated | Application | ELISA, IF, IHC |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human Fasciculation and elongation protein zeta-1 protein (12-200AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q99689 |
Uniprot Id
Q99689
Target Species
Human
Target Name
FEZ1
Target Full Name
Fasciculation and elongation protein zeta-1
Target Function
May be involved in axonal outgrowth as component of the network of molecules that regulate cellular morphology and axon guidance machinery. Able to restore partial locomotion and axonal fasciculation to C.elegans unc-76 mutants in germline transformation experiments. May participate in the transport of mitochondria and other cargos along microtubules.
Target Subcellular Location
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cell membrane.
Target Protein Families
Zygin family
Target Tissue Specificity
Mainly expressed in brain.
Target Synonyms
FEZ1Fasciculation and elongation protein zeta-1; Zygin I; Zygin-1
Target Background
This gene is an ortholog of the C. elegans unc-76 gene, which is necessary for normal axonal bundling and elongation within axon bundles. Expression of this gene in C. elegans unc-76 mutants can restore to the mutants partial locomotion and axonal fasciculation, suggesting that it also functions in axonal outgrowth. The N-terminal half of the gene product is highly acidic. Alternatively spliced transcript variants encoding different isoforms of this protein have been described.
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