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The antibody against CCDC155 was raised in rabbit using the Recombinant Human Protein KASH5 protein (1-300AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA.
The antibody against CCDC155 was raised in rabbit using the Recombinant Human Protein KASH5 protein (1-300AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA.
$299.00
| Cat.No | ADC-19213A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | CCDC155 |
| Target Synonyms | CCDC155 antibody; KASH5 antibody; Protein KASH5 antibody; Coiled-coil domain-containing protein 155 antibody; KASH domain-containing protein 5 antibody | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | >95%, Protein G purified |
| Conjugate | Non-conjugated | Application | ELISA |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human Protein KASH5 protein (1-300AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q8N6L0 |
Uniprot Id
Q8N6L0
Target Species
Human
Target Name
KASH5
Target Full Name
Protein KASH5
Target Function
As a component of the LINC (LInker of Nucleoskeleton and Cytoskeleton) complex, involved in the connection between the nuclear lamina and the cytoskeleton. The nucleocytoplasmic interactions established by the LINC complex play an important role in the transmission of mechanical forces across the nuclear envelope and in nuclear movement and positioning. Required for telomere attachment to nuclear envelope in the prophase of meiosis and for rapid telomere prophase movements implicating a SUN1/2:KASH5 LINC complex in which SUN1 and SUN2 seem to act at least partial redundantly. Required for homolog pairing during meiotic prophase in spermatocytes and probably oocytes. Essential for male and female gametogenesis. Recruits cytoplasmic dynein to telomere attachment sites at the nuclear envelope in spermatocytes. In oocytes is involved in meiotic resumption and spindle formation.
Target Subcellular Location
Nucleus outer membrane; Single-pass type IV membrane protein; Cytoplasmic side. Nucleus. Chromosome, telomere.
Target Synonyms
CCDC155; KASH5; Protein KASH5; Coiled-coil domain-containing protein 155; KASH domain-containing protein 5
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