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The antibody against COA6 was raised in rabbit using the Recombinant Human Cytochrome c oxidase assembly factor 6 homolog protein (1-125AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.
The antibody against COA6 was raised in rabbit using the Recombinant Human Cytochrome c oxidase assembly factor 6 homolog protein (1-125AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.
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Immunohistochemistry of paraffin-embedded human adrenal gland tissue using COA6 Antibody at dilution of 1:100
| Cat.No | ADC-20045A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | COA6 |
| Target Synonyms | COA6 antibody; C1orf31Cytochrome c oxidase assembly factor 6 homolog antibody | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | >95%, Protein G purified |
| Conjugate | Non-conjugated | Application | ELISA, IHC |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human Cytochrome c oxidase assembly factor 6 homolog protein (1-125AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q5JTJ3 |
Uniprot Id
Q5JTJ3
Target Species
Human
Target Name
COA6
Target Full Name
Cytochrome c oxidase assembly factor 6 homolog
Target Function
Involved in the maturation of the mitochondrial respiratory chain complex IV subunit MT-CO2/COX2. Thereby, may regulate early steps of complex IV assembly. Mitochondrial respiratory chain complex IV or cytochrome c oxidase is the component of the respiratory chain that catalyzes the transfer of electrons from intermembrane space cytochrome c to molecular oxygen in the matrix and as a consequence contributes to the proton gradient involved in mitochondrial ATP synthesis. May also be required for efficient formation of respiratory supercomplexes comprised of complexes III and IV.
Target Involvement
Cardioencephalomyopathy, fatal infantile, due to cytochrome c oxidase deficiency 4 (CEMCOX4)
Target Subcellular Location
Mitochondrion intermembrane space.
Target Protein Families
Cytochrome c oxidase subunit 6B family
Target Synonyms
COA6; C1orf31Cytochrome c oxidase assembly factor 6 homolog
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