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Rabbit anti-Human ADRB3 Polyclonal Antibody

The antibody against ADRB3 was raised in rabbit using the Synthetic peptide of Human ADRB3 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC.

ADC-26290A

The antibody against ADRB3 was raised in rabbit using the Synthetic peptide of Human ADRB3 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC.

$299.00

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Specifications


Cat.No ADC-26290A ClonalityPolyclonal
Host SpeciesRabbitTarget NameADRB3
Target SynonymsADRB3; ADRB3R; B3AR; Beta-3 adrenergic receptor; Beta-3 adrenoreceptor; Beta-3 adrenoceptorFormLiquid
Species ReactivityHuman, MouseIsotypeIgG
Storage Buffer0.05% NaN3, 40% Glycerol., pH7.4 PBSPurification MethodAntigen affinity purified
ConjugateNon-conjugatedApplicationELISA, IHC, WB
StorageUpon receipt

Immunogen Information


Immunogen DescriptionSynthetic peptide of Human ADRB3Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDP13945
Background Information
  • Uniprot Id

    P13945

  • Target Species

    Human

  • Target Name

    ADRB3

  • Target Full Name

    Beta-3 adrenergic receptor

  • Target Function

    Beta-adrenergic receptors mediate the catecholamine-induced activation of adenylate cyclase through the action of G proteins. Beta-3 is involved in the regulation of lipolysis and thermogenesis.

  • Target Subcellular Location

    Cell membrane; Multi-pass membrane protein.

  • Target Protein Families

    G-protein coupled receptor 1 family, Adrenergic receptor subfamily, ADRB3 sub-subfamily

  • Target Tissue Specificity

    Expressed mainly in adipose tissues.

  • Target Research Area

    Cardiovascular

  • Target Synonyms

    ADRB3; ADRB3R; B3AR; Beta-3 adrenergic receptor; Beta-3 adrenoreceptor; Beta-3 adrenoceptor

  • Target Background

    The protein encoded by this gene belongs to the family of beta adrenergic receptors, which mediate catecholamine-induced activation of adenylate cyclase through the action of G proteins. This receptor is located mainly in the adipose tissue and is involved in the regulation of lipolysis and thermogenesis. Obesity and bodyweight-related disorders are correlated with certain polymorphisms in three subtypes of beta-adrenoceptor, among them, the ADRB3 gene.

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