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The antibody against AIFM3 was raised in rabbit using the Fusion protein of Human AIFM3 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC.
The antibody against AIFM3 was raised in rabbit using the Fusion protein of Human AIFM3 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC.
$299.00
| Cat.No | ADC-30566A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | AIFM3 |
| Form | Liquid | Species Reactivity | Human, Mouse |
| Isotype | IgG | Storage Buffer | 0.05% NaN3, 40% Glycerol., pH7.4 PBS |
| Purification Method | Antigen affinity purified | Conjugate | Non-conjugated |
| Application | ELISA, IHC, WB | Storage | Upon receipt |
| Immunogen Description | Fusion protein of Human AIFM3 | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q96NN9 |
Uniprot Id
Q96NN9
Target Species
Human
Target Name
AIFM3
Target Full Name
Apoptosis-inducing factor 3
Target Function
Induces apoptosis through a caspase dependent pathway. Reduces mitochondrial membrane potential.
Target Subcellular Location
Mitochondrion. Note=Does not translocate to the nucleus upon induction of apoptosis.
Target Protein Families
FAD-dependent oxidoreductase family
Target Tissue Specificity
Ubiquitous. Expressed in bone marrow, cerebral cortex, liver, ovary, thymus, thyroid gland and tongue (at protein level).
Target Synonyms
AIFL; Aifm3; AIFM3_HUMAN; Apoptosis inducing factor 3; Apoptosis inducing factor like; Apoptosis inducing factor like protein; Apoptosis inducing factor; mitochondrion associated; Apoptosis-inducing factor 3; Apoptosis-inducing factor-like protein; FLJ30473; FLJ45137
Target Background
Predicted to enable several functions, including 2 iron, 2 sulfur cluster binding activity; flavin adenine dinucleotide binding activity; and metal ion binding activity. Involved in execution phase of apoptosis. Located in cytosol; endoplasmic reticulum; and mitochondrial inner membrane.
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