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Rabbit anti-Human HSPB6 Polyclonal Antibody

The antibody against HSPB6 was raised in rabbit using the Synthesized peptide derived from Human HSP20 around the non-phosphorylation site of S16. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on IHC, ELISA.

ADC-36400A

The antibody against HSPB6 was raised in rabbit using the Synthesized peptide derived from Human HSP20 around the non-phosphorylation site of S16. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on IHC, ELISA.

$167.00

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Specifications


Cat.No ADC-36400A ClonalityPolyclonal
Host SpeciesRabbitTarget NameHSPB6
FormLiquidSpecies ReactivityHuman, Mouse, Rat
IsotypeIgGStorage Buffer0.5% BSA and 0.02% sodium azide., Liquid in PBS containing 50% glycerol
Purification MethodThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.ConjugateNon-conjugated
ApplicationELISA, IHCStorageUpon receipt

Immunogen Information


Immunogen DescriptionSynthesized peptide derived from Human HSP20 around the non-phosphorylation site of S16.Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDO14558
Background Information
  • Uniprot Id

    O14558

  • Target Species

    Human

  • Target Name

    HSPB6

  • Target Full Name

    Heat shock protein beta-6

  • Target Function

    Small heat shock protein which functions as a molecular chaperone probably maintaining denatured proteins in a folding-competent state. Seems to have versatile functions in various biological processes. Plays a role in regulating muscle function such as smooth muscle vasorelaxation and cardiac myocyte contractility. May regulate myocardial angiogenesis implicating KDR. Overexpression mediates cardioprotection and angiogenesis after induced damage. Stabilizes monomeric YWHAZ thereby supporting YWHAZ chaperone-like activity.

  • Target Subcellular Location

    Cytoplasm. Nucleus. Secreted.

  • Target Protein Families

    Small heat shock protein (HSP20) family

  • Target Synonyms

    epididymis luminal protein 55; FLJ32389; Heat shock 20 kDa like protein p20 ; Heat shock 20 kDa-like protein p20; Heat shock protein alpha crystallin related B6; Heat shock protein beta 6 ; Heat shock protein beta-6; Heat shock protein; 20-KD; Heat-shock 27-KD protein 6; HEL55; Hsp20; HspB6; HSPB6_HUMAN

  • Target Background

    This locus encodes a heat shock protein. The encoded protein likely plays a role in smooth muscle relaxation.

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