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Rabbit anti-Human POU3F4 Polyclonal Antibody

The antibody against POU3F4 was raised in rabbit using the Recombinant Human POU domain, class 3, transcription factor 4 protein (22-134AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.

ADC-04253A

The antibody against POU3F4 was raised in rabbit using the Recombinant Human POU domain, class 3, transcription factor 4 protein (22-134AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.

$299.00

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Specifications


Cat.No ADC-04253A ClonalityPolyclonal
Host SpeciesRabbitTarget NamePOU3F4
FormLiquidSpecies ReactivityHuman
IsotypeIgGStorage Buffer0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4
Purification Method>95%, Protein G purifiedConjugateNon-conjugated
ApplicationELISA, IHCStorageUpon receipt

Immunogen Information


Immunogen DescriptionRecombinant Human POU domain, class 3, transcription factor 4 protein (22-134AA)Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDP49335
Background Information
  • Uniprot Id

    P49335

  • Target Species

    Human

  • Target Name

    POU3F4

  • Target Full Name

    POU domain, class 3, transcription factor 4

  • Target Function

    Probable transcription factor which exert its primary action widely during early neural development and in a very limited set of neurons in the mature brain.

  • Target Involvement

    Deafness, X-linked, 2 (DFNX2)

  • Target Subcellular Location

    Nucleus.

  • Target Protein Families

    POU transcription factor family, Class-3 subfamily

  • Target Tissue Specificity

    Brain specific.

  • Target Synonyms

    Brain specific homeobox POU domain protein 4; Brain-4; Brain-specific homeobox/POU domain protein 4; BRAIN4; Brn-4; BRN4; class 3; DFN3; DFNX2; Oct-9; Octamer-binding protein 9; Octamer-binding transcription factor 9; OTF-9; OTF9; PO3F4_HUMAN; POU class 3 homeobox 4; POU domain; POU domain class 3 transcription factor 4; Pou3f4; transcription factor 4

  • Target Background

    This gene encodes a member of the POU-III class of neural transcription factors. This family member plays a role in inner ear development. The protein is thought to be involved in the mediation of epigenetic signals which induce striatal neuron-precursor differentiation. Mutations in this gene are associated with X chromosome-linked nonsyndromic mixed deafness.

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