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The antibody against MS4A12 was raised in rabbit using the Recombinant Human Membrane-spanning 4-domains subfamily A member 12 protein (1-90AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC.
The antibody against MS4A12 was raised in rabbit using the Recombinant Human Membrane-spanning 4-domains subfamily A member 12 protein (1-90AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC.
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Immunohistochemistry of paraffin-embedded human colon cancer using MS4A12 Antibody at dilution of 1:100
| Cat.No | ADC-40299A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | MS4A12 |
| Target Synonyms | MS4A12; Membrane-spanning 4-domains subfamily A member 12 | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. | Purification Method | Antigen affinity purified |
| Conjugate | Non-conjugated | Application | ELISA, IHC |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human Membrane-spanning 4-domains subfamily A member 12 protein (1-90AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q9NXJ0 |
Uniprot Id
Q9NXJ0
Target Species
Human
Target Name
MS4A12
Target Full Name
Membrane-spanning 4-domains subfamily A member 12
Target Function
May be involved in signal transduction as a component of a multimeric receptor complex.
Target Subcellular Location
Membrane; Multi-pass membrane protein.
Target Protein Families
MS4A family
Target Synonyms
MS4A12; Membrane-spanning 4-domains subfamily A member 12
Target Background
The protein encoded by this gene is a cell surface protein found primarily in the apical membrane of colonocytes. Silencing of this gene in colon cancer cells inhibits the proliferation, cell motility, and chemotactic invasion of cells. This gene is part of a cluster of similar genes found on chromosome 11. Two transcript variants encoding different isoforms have been found for this gene.
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