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Rabbit anti-Human NFE2L3 Polyclonal Antibody

The antibody against NFE2L3 was raised in rabbit using the Synthesized peptide derived from internal of Human NFE2L3. as the immunogen. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on ELISA, WB.

ADC-40727A

The antibody against NFE2L3 was raised in rabbit using the Synthesized peptide derived from internal of Human NFE2L3. as the immunogen. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on ELISA, WB.

$297.00

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Specifications


Cat.No ADC-40727A ClonalityPolyclonal
Host SpeciesRabbitTarget NameNFE2L3
FormLiquidSpecies ReactivityHuman
Storage BufferPH 7.4, 0.02% sodium azide and 50% glycerol., 150mM NaCl, Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+)Purification MethodThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
ApplicationELISA, WBStorageUpon receipt

Immunogen Information


Immunogen DescriptionSynthesized peptide derived from internal of Human NFE2L3.Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDQ9Y4A8
Background Information
  • Uniprot Id

    Q9Y4A8

  • Target Species

    Human

  • Target Name

    NFE2L3

  • Target Full Name

    Nuclear factor erythroid 2-related factor 3

  • Target Function

    Activates erythroid-specific, globin gene expression.

  • Target Subcellular Location

    Nucleus.

  • Target Protein Families

    BZIP family, CNC subfamily

  • Target Tissue Specificity

    Highly expressed in human placenta and also in B-cell and monocyte cell lines. Low expression in heart, brain, lung, skeletal muscle, kidney and pancreas.

  • Target Synonyms

    NFE2L3; NRF3; Nuclear factor erythroid 2-related factor 3; NF-E2-related factor 3; NFE2-related factor 3; Nuclear factor; erythroid derived 2; like 3

  • Target Background

    This gene encodes a member of the cap 'n' collar basic-region leucine zipper family of transcription factors. The encoded protein heterodimerizes with small musculoaponeurotic fibrosarcoma factors to bind antioxidant response elements in target genes. This protein is a membrane bound glycoprotein that is targeted to the endoplasmic reticulum and the nuclear envelope. Pseudogenes of this gene are found on chromosomes 16, 17, and 18.

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