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The antibody against EIF2B4 was raised in rabbit using the Synthesized peptide derived from internal of Human EIF2B4. as the immunogen. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on ELISA, WB.
The antibody against EIF2B4 was raised in rabbit using the Synthesized peptide derived from internal of Human EIF2B4. as the immunogen. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on ELISA, WB.
$297.00
Western blot analysis of extracts from HepG2 cells and LOVO cells, using EIF2B4 antibody.
| Cat.No | ADC-40852A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | EIF2B4 |
| Form | Liquid | Species Reactivity | Human |
| Storage Buffer | PH 7.4, 0.02% sodium azide and 50% glycerol., 150mM NaCl, Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+) | Purification Method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Application | ELISA, WB | Storage | Upon receipt |
| Immunogen Description | Synthesized peptide derived from internal of Human EIF2B4. | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q9UI10 |
Uniprot Id
Q9UI10
Target Species
Human
Target Name
EIF2B4
Target Full Name
Translation initiation factor eIF2B subunit delta
Target Function
Catalyzes the exchange of eukaryotic initiation factor 2-bound GDP for GTP.
Target Involvement
Leukodystrophy with vanishing white matter (VWM)
Target Protein Families
EIF-2B alpha/beta/delta subunits family
Target Synonyms
EI2BD_HUMAN; EIF 2B; eIF 2B GDP GTP exchange factor subunit delta; eIF-2B GDP-GTP exchange factor subunit delta; Eif2b4; EIF2Bdelta; eukaryotic translation initiation factor 2B subunit 4; Translation initiation factor eIF-2B subunit delta
Target Background
Eukaryotic initiation factor 2B (EIF2B), which is necessary for protein synthesis, is a GTP exchange factor composed of five different subunits. The protein encoded by this gene is the fourth, or delta, subunit. Defects in this gene are a cause of leukoencephalopathy with vanishing white matter (VWM) and ovarioleukodystrophy. Multiple transcript variants encoding different isoforms have been found for this gene.
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