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The antibody against SLC6A8 was raised in rabbit using the Synthesized peptide derived from C-terminal of Human SLC6A8. as the immunogen. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on ELISA, WB.
The antibody against SLC6A8 was raised in rabbit using the Synthesized peptide derived from C-terminal of Human SLC6A8. as the immunogen. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on ELISA, WB.
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Western blot analysis of extracts from HuvEc cells, using SLC6A8 antibody.
| Cat.No | ADC-40904A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | SLC6A8 |
| Target Synonyms | creatine), member 8. antibody; Solute carrier family 6 member 8 antibody | Form | Liquid |
| Species Reactivity | Human | Storage Buffer | PH 7.4, 0.02% sodium azide and 50% glycerol., 150mM NaCl, Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+) |
| Purification Method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. | Application | ELISA, WB |
| Storage | Upon receipt |
| Immunogen Description | Synthesized peptide derived from C-terminal of Human SLC6A8. | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | P48029 |
Uniprot Id
P48029
Target Species
Human
Target Name
SLC6A8
Target Full Name
Sodium- and chloride-dependent creatine transporter 1
Target Function
Required for the uptake of creatine in muscles and brain.
Target Involvement
Cerebral creatine deficiency syndrome 1 (CCDS1)
Target Subcellular Location
Membrane; Multi-pass membrane protein.
Target Protein Families
Sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family, SLC6A8 subfamily
Target Tissue Specificity
Predominantly expressed in skeletal muscle and kidney. Also found in brain, heart, colon, testis and prostate.
Target Synonyms
SLC6A 8; SLC6A8; Creatine transporter 1; Creatine transporter SLC6A8; CRT; CRTR; CT 1; CT1; MGC87396; SC6A8_HUMAN; Slc6a8; Sodium and chloride-dependent creatine transporter 1; Sodium- and chloride-dependent creatine transporter 1; Solute carrier family 6 (neurotransmitter transporter, creatine), member 8.; Solute carrier family 6 member 8
Target Background
The protein encoded by this gene is a plasma membrane protein whose function is to transport creatine into and out of cells. Defects in this gene can result in X-linked creatine deficiency syndrome. Multiple transcript variants encoding different isoforms have been found for this gene.
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