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Rabbit anti-Human MSX2 Polyclonal Antibody

The antibody against MSX2 was raised in rabbit using the Synthesized peptide derived from Internal of Human MSX2. as the immunogen. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on ELISA, WB.

ADC-41182A

The antibody against MSX2 was raised in rabbit using the Synthesized peptide derived from Internal of Human MSX2. as the immunogen. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on ELISA, WB.

$297.00

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Specifications


Cat.No ADC-41182A ClonalityPolyclonal
Host SpeciesRabbitTarget NameMSX2
FormLiquidSpecies ReactivityHuman, Mouse
Storage BufferPH 7.4, 0.02% sodium azide and 50% glycerol., 150mM NaCl, Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+)Purification MethodThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
ApplicationELISA, WBStorageUpon receipt

Immunogen Information


Immunogen DescriptionSynthesized peptide derived from Internal of Human MSX2.Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDP35548
Background Information
  • Uniprot Id

    P35548

  • Target Species

    Human

  • Target Name

    MSX2

  • Target Full Name

    Homeobox protein MSX-2

  • Target Function

    Acts as a transcriptional regulator in bone development. Represses the ALPL promoter activity and antagonizes the stimulatory effect of DLX5 on ALPL expression during osteoblast differentiation. Probable morphogenetic role. May play a role in limb-pattern formation. In osteoblasts, suppresses transcription driven by the osteocalcin FGF response element (OCFRE). Binds to the homeodomain-response element of the ALPL promoter.

  • Target Involvement

    Parietal foramina 1 (PFM1); Parietal foramina with cleidocranial dysplasia (PFMCCD); Craniosynostosis 2 (CRS2)

  • Target Subcellular Location

    Nucleus.

  • Target Protein Families

    Msh homeobox family

  • Target Synonyms

    CRS 2; CRS2; FPP; Homeo box msh like 2; Homeobox protein Hox-8; Homeobox protein MSX 2; Homeobox protein MSX-2; Homeobox protein MSX2; Hox 8; Hox8; MSH; Msh homeo box 2; Msh homeo box homolog; Msh homeo box homolog 2; Msh homeobox 2; Msh homeobox homolog 2; Msx 2; MSX2; MSX2_HUMAN; Parietal foramina 1; PFM 1; PFM; PFM1

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