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The antibody against HSPB2 was raised in rabbit using the Synthesized peptide derived from internal of Human HSPB2. as the immunogen. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on ELISA, WB, IF.
The antibody against HSPB2 was raised in rabbit using the Synthesized peptide derived from internal of Human HSPB2. as the immunogen. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on ELISA, WB, IF.
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Western blot analysis of extracts from HepG2 cells and HeLa cells, using HSPB2 antibody.
Immunofluorescence analysis of A549 cells, using HSPB2 antibody.2
| Cat.No | ADC-41636A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | HSPB2 |
| Form | Liquid | Species Reactivity | Human, Mouse, Rat |
| Storage Buffer | PH 7.4, 0.02% sodium azide and 50% glycerol., 150mM NaCl, Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+) | Purification Method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Application | ELISA, IF, WB | Storage | Upon receipt |
| Immunogen Description | Synthesized peptide derived from internal of Human HSPB2. | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q16082 |
Uniprot Id
Q16082
Target Species
Human
Target Name
HSPB2
Target Full Name
Heat shock protein beta-2
Target Function
May regulate the kinase DMPK.
Target Subcellular Location
Cytoplasm. Nucleus. Note=Localizes to nuclear foci.
Target Protein Families
Small heat shock protein (HSP20) family
Target Tissue Specificity
Expressed preferentially in skeletal muscle and heart but not in the lens.
Target Research Area
Signal Transduction
Target Synonyms
DMPK-binding protein; Heat shock 27kD protein 2; Heat shock 27kDa protein 2; Heat shock protein beta-2; Heat-shock protein beta-2; Hs.78846; HSP27; HspB2; HSPB2_HUMAN; LOH11CR1K; MGC133245; MKBP
Target Background
The protein encoded by this gene belongs to the superfamily of small heat-shock proteins containing a conservative alpha-crystallin domain at the C-terminal part of the molecule. The protein is expressed preferentially in the heart and skeletal muscle. This protein regulates Myotonic Dystrophy Protein Kinase, which plays an important role in maintenance of muscle structure and function.
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