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The antibody against CLK4 was raised in rabbit using the Synthesized peptide derived from internal of Human CLK4. as the immunogen. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on ELISA, WB.
The antibody against CLK4 was raised in rabbit using the Synthesized peptide derived from internal of Human CLK4. as the immunogen. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on ELISA, WB.
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Western blot analysis of extracts from HT-29 cells, using CLK4 antibody.
| Cat.No | ADC-41798A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | CLK4 |
| Form | Liquid | Species Reactivity | Human, Mouse |
| Storage Buffer | PH 7.4, 0.02% sodium azide and 50% glycerol., 150mM NaCl, Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+) | Purification Method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Application | ELISA, WB | Storage | Upon receipt |
| Immunogen Description | Synthesized peptide derived from internal of Human CLK4. | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q9HAZ1 |
Uniprot Id
Q9HAZ1
Target Species
Human
Target Name
CLK4
Target Full Name
Dual specificity protein kinase CLK4
Target Function
Dual specificity kinase acting on both serine/threonine and tyrosine-containing substrates. Phosphorylates serine- and arginine-rich (SR) proteins of the spliceosomal complex and may be a constituent of a network of regulatory mechanisms that enable SR proteins to control RNA splicing. Phosphorylates SRSF1 and SRSF3. Required for the regulation of alternative splicing of MAPT/TAU. Regulates the alternative splicing of tissue factor (F3) pre-mRNA in endothelial cells.
Target Subcellular Location
Nucleus.
Target Protein Families
Protein kinase superfamily, CMGC Ser/Thr protein kinase family, Lammer subfamily
Target Tissue Specificity
Expressed in liver, kidney, heart, muscle, brain and endothelial cells.
Target Synonyms
AI987988; C85119; CDC like kinase 4; CDC-like kinase 4; CLK4; CLK4_HUMAN; DKFZp686A20267; Dual specificity protein kinase CLK4; OTTMUSP00000005756,; OTTMUSP00000005757; OTTMUSP00000041113; Protein serine threonine kinase Clk4; RP23-9N7.1
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