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The antibody against COQ8B was raised in rabbit using the Synthesized peptide derived from internal of Human ADCK4. as the immunogen. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on ELISA, WB, IF.
The antibody against COQ8B was raised in rabbit using the Synthesized peptide derived from internal of Human ADCK4. as the immunogen. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on ELISA, WB, IF.
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Western blot analysis of extracts from HepG2 cells, using ADCK4 antibody.
Immunofluorescence analysis of A549 cells, using ADCK4 antibody.2
| Cat.No | ADC-41840A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | COQ8B |
| Target Synonyms | COQ8B; ADCK4; Atypical kinase COQ8B, mitochondrial; AarF domain-containing protein kinase 4; Coenzyme Q protein 8B | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Storage Buffer | PH 7.4, 0.02% sodium azide and 50% glycerol., 150mM NaCl, Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+) |
| Purification Method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. | Application | ELISA, IF, WB |
| Storage | Upon receipt |
| Immunogen Description | Synthesized peptide derived from internal of Human ADCK4. | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q96D53 |
Uniprot Id
Q96D53
Target Species
Human
Target Name
COQ8B
Target Full Name
Atypical kinase COQ8B, mitochondrial
Target Function
Atypical kinase involved in the biosynthesis of coenzyme Q, also named ubiquinone, an essential lipid-soluble electron transporter for aerobic cellular respiration. Its substrate specificity is unclear: does not show any protein kinase activity. Probably acts as a small molecule kinase, possibly a lipid kinase that phosphorylates a prenyl lipid in the ubiquinone biosynthesis pathway. Required for podocyte migration.
Target Involvement
Nephrotic syndrome 9 (NPHS9)
Target Subcellular Location
Mitochondrion membrane; Single-pass membrane protein. Cytoplasm, cytosol. Cell membrane.
Target Protein Families
Protein kinase superfamily, ADCK protein kinase family
Target Tissue Specificity
Widely expressed, including renal podocytes.
Target Synonyms
COQ8B; ADCK4; Atypical kinase COQ8B, mitochondrial; AarF domain-containing protein kinase 4; Coenzyme Q protein 8B
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