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The antibody against Map2k5 was raised in rabbit using the Peptide sequence around aa. 311-315(K-T-Y-V-G ) derived from Rat MEK5. as the immunogen. Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide This antibody has been validated on ELISA, WB.
The antibody against Map2k5 was raised in rabbit using the Peptide sequence around aa. 311-315(K-T-Y-V-G ) derived from Rat MEK5. as the immunogen. Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide This antibody has been validated on ELISA, WB.
$297.00
Western blot analysis of extract from rat brain and mouse brain tissue using MEK5 Antibody
| Cat.No | ADC-43203A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | MAP2K5 |
| Form | Liquid | Species Reactivity | Human, Mouse, Rat |
| Storage Buffer | PH 7.4, 0.02% sodium azide and 50% glycerol., 150mM NaCl, Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+) | Purification Method | Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide. |
| Application | ELISA, WB | Storage | Upon receipt |
| Immunogen Description | Peptide sequence around aa. 311-315(K-T-Y-V-G ) derived from Rat MEK5. | Target Species | Rattus norvegicus (Rat) |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q62862 |
Uniprot Id
Q62862
Target Species
Rat
Target Name
MAP2K5
Target Full Name
Dual specificity mitogen-activated protein kinase kinase 5
Target Function
Acts as a scaffold for the formation of a ternary MAP3K2/MAP3K3-MAP3K5-MAPK7 signaling complex. Activation of this pathway appears to play a critical role in protecting cells from stress-induced apoptosis, neuronal survival and cardiac development and angiogenesis.
Target Subcellular Location
[Isoform Beta]: Cytoplasm, cytosol.; [Isoform Alpha-1]: Membrane. Note=The alternatively spliced exon in alpha isoform resemble conserved sequences that mediate interactions with the cytoskeleton, thereby explaining the differential localization.; [Isoform Alpha-2]: Membrane. Note=The alternatively spliced exon in alpha isoform resemble conserved sequences that mediate interactions with the cytoskeleton, thereby explaining the differential localization.
Target Protein Families
Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase subfamily
Target Tissue Specificity
MEK5 beta is ubiquitously distributed with highest levels in the liver, whereas MEK5 alpha is expressed only in liver and brain.
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