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The antibody against RMDN3 was raised in rabbit using the Recombinant Human Regulator of microtubule dynamics protein 3 protein (1-470AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.
The antibody against RMDN3 was raised in rabbit using the Recombinant Human Regulator of microtubule dynamics protein 3 protein (1-470AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.
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Immunohistochemistry of paraffin-embedded human lung cancer using RMDN3 Antibody at dilution of 1:100
Immunohistochemistry of paraffin-embedded human breast cancer using RMDN3 Antibody at dilution of 1:1002
| Cat.No | ADC-45457A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | RMDN3 |
| Form | Liquid | Species Reactivity | Human |
| Isotype | IgG | Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 |
| Purification Method | >95%, Protein G purified | Conjugate | Non-conjugated |
| Application | ELISA, IHC | Storage | Upon receipt |
| Immunogen Description | Recombinant Human Regulator of microtubule dynamics protein 3 protein (1-470AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q96TC7 |
Uniprot Id
Q96TC7
Target Species
Human
Target Name
RMDN3
Target Full Name
Regulator of microtubule dynamics protein 3
Target Function
Involved in cellular calcium homeostasis regulation. May participate in differentiation and apoptosis of keratinocytes. Overexpression induces apoptosis.
Target Subcellular Location
Mitochondrion outer membrane; Single-pass membrane protein. Cytoplasm. Nucleus. Cytoplasm, cytoskeleton, spindle. Cytoplasm, cytoskeleton, spindle pole.
Target Protein Families
RMDN family
Target Tissue Specificity
Present at high level in epidermis and seminiferous epithelium: while basal cells in the epidermis and spermatogonia show no perceptible amount, keratinocytes of suprabasal layers and differentiating first-order spermatocytes up to spermatids exhibit high
Target Research Area
Apoptosis
Target Synonyms
RMDN3; FAM82A2; FAM82C; PTPIP51; hucep-10; UNQ3122/PRO10274; Regulator of microtubule dynamics protein 3; RMD-3; hRMD-3; Cerebral protein 10; Protein FAM82A2; Protein FAM82C; Protein tyrosine phosphatase-interacting protein 51; TCPTP-interacting protein 51
Target Background
Enables microtubule binding activity. Involved in cellular calcium ion homeostasis. Located in several cellular components, including intercellular bridge; mitochondrial outer membrane; and spindle.
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