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Rabbit anti-Human ST8SIA3 Polyclonal Antibody

The antibody against ST8SIA3 was raised in rabbit using the Human ST8SIA3 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC.

ADC-47049A

The antibody against ST8SIA3 was raised in rabbit using the Human ST8SIA3 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC.

$600.00

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Specifications


Cat.No ADC-47049A ClonalityPolyclonal
Host SpeciesRabbitTarget NameST8SIA3
Target Synonyms3-Gal-beta-1, 4-GlcNAc-R:alpha 2, 8-sialyltransferase 3; Sialyltransferase 8C; SIAT8-C; Sialyltransferase St8Sia III; ST8SiaIII, 8-sialyltransferase 8C; Alpha-2, 8-sialyltransferase III; ST8 alpha-N-acetyl-neuraminide alpha-2, 8-sialyltransferase; Alpha-2, ST8SIA3; SIAT8C; Sia-alpha-2FormLiquid
Species ReactivityHuman, Mouse, RatIsotypeIgG
Storage Buffer50% Glycerol, Avoid freeze / thaw cycles., PBS with 0.1% Sodium AzidePurification MethodAntigen affinity purified
ConjugateNon-conjugatedApplicationELISA, IHC, WB
StorageUpon receipt

Immunogen Information


Immunogen DescriptionHuman ST8SIA3Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDO43173
Background Information
  • Uniprot Id

    O43173

  • Target Species

    Human

  • Target Name

    ST8SIA3

  • Target Full Name

    Alpha-N-acetylneuraminate alpha-2,8-sialyltransferase ST8SIA3

  • Target Function

    Catalyzes the transfer of sialic acid from a CMP-linked sialic acid donor onto the terminal sialic acid of an acceptor through alpha-2,8-linkages. Is active with alpha-2,3-linked, alpha-2,6-linked and alpha-2,8-linked sialic acid of N-linked oligosaccharides of glycoproteins and glycolipids. Displays preference for substrates with alpha-2,3-linked terminal sialic acid. It can form polysialic acid in vitro directly on alpha-2,3-, alpha-2,6-, or alpha-2,8-linked sialic acid.

  • Target Subcellular Location

    Golgi apparatus membrane; Single-pass type II membrane protein.

  • Target Protein Families

    Glycosyltransferase 29 family

  • Target Tissue Specificity

    Expressed in fetal and adult brain and fetal liver.

  • Target Synonyms

    ST8SIA3; SIAT8C; Sia-alpha-2,3-Gal-beta-1,4-GlcNAc-R:alpha 2,8-sialyltransferase; Alpha-2,8-sialyltransferase 8C; Alpha-2,8-sialyltransferase III; ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3; Sialyltransferase 8C; SIAT8-C; Sialyltransferase St8Sia III; ST8SiaIII

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