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The antibody against HPSE2 was raised in rabbit using the Human HPSE2 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB.
The antibody against HPSE2 was raised in rabbit using the Human HPSE2 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB.
$600.00
| Cat.No | ADC-48317A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | HPSE2 |
| Target Synonyms | HPSE2 antibody; HPA2 antibody; Inactive heparanase-2 antibody; Hpa2 antibody | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, Avoid freeze / thaw cycles., PBS with 0.02% sodium azide | Purification Method | Antigen affinity purified |
| Conjugate | Non-conjugated | Application | ELISA, WB |
| Storage | Upon receipt |
| Immunogen Description | Human HPSE2 | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q8WWQ2 |
Uniprot Id
Q8WWQ2
Target Species
Human
Target Name
HPSE2
Target Full Name
Inactive heparanase-2
Target Function
Binds heparin and heparan sulfate with high affinity, but lacks heparanase activity. Inhibits HPSE, possibly by competing for its substrates (in vitro).
Target Involvement
Urofacial syndrome 1 (UFS1)
Target Subcellular Location
Secreted, extracellular space, extracellular matrix.
Target Protein Families
Glycosyl hydrolase 79 family
Target Tissue Specificity
Widely expressed, with the highest expression in brain, mammary gland, prostate, small intestine, testis and uterus. In the central nervous system, expressed in the spinal chord, caudate nucleus, thalamus, substantia nigra, medulla oblongata, putamen and
Target Synonyms
HPSE2; HPA2; Inactive heparanase-2; Hpa2
Target Background
This gene encodes a heparanase enzyme. The encoded protein is a endoglycosidase that degrades heparin sulfate proteoglycans located on the extracellular matrix and cell surface. This protein may be involved in biological processes involving remodeling of the extracellular matrix including angiogenesis and tumor progression. Alternate splicing results in multiple transcript variants.
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