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Rabbit anti-Human CSRP2 Polyclonal Antibody

The antibody against CSRP2 was raised in rabbit using the Human CSRP2 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB.

ADC-48843A

The antibody against CSRP2 was raised in rabbit using the Human CSRP2 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB.

$600.00

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Specifications


Cat.No ADC-48843A ClonalityPolyclonal
Host SpeciesRabbitTarget NameCSRP2
FormLiquidSpecies ReactivityHuman, Mouse, Rat
IsotypeIgGStorage Buffer50% Glycerol, Avoid freeze / thaw cycles., PBS with 0.1% Sodium Azide
Purification MethodAntigen affinity purifiedConjugateNon-conjugated
ApplicationELISA, WBStorageUpon receipt

Immunogen Information


Immunogen DescriptionHuman CSRP2Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDQ16527
Background Information
  • Uniprot Id

    Q16527

  • Target Species

    Human

  • Target Name

    CSRP2

  • Target Full Name

    Cysteine and glycine-rich protein 2

  • Target Function

    Drastically down-regulated in response to PDGF-BB or cell injury, that promote smooth muscle cell proliferation and dedifferentiation. Seems to play a role in the development of the embryonic vascular system.

  • Target Subcellular Location

    Nucleus.

  • Target Tissue Specificity

    Highly expressed in the aorta, but not in heart and skeletal muscle.

  • Target Synonyms

    CRP2; CSRP2; CSRP2_HUMAN; Cysteine and glycine rich protein 2; Cysteine and glycine-rich protein 2; Cysteine rich protein 2; Cysteine-rich protein 2; LIM domain only protein 5; LMO-5; LMO5; SmLIM; Smooth muscle cell LIM protein

  • Target Background

    CSRP2 is a member of the CSRP family of genes, encoding a group of LIM domain proteins, which may be involved in regulatory processes important for development and cellular differentiation. CRP2 contains two copies of the cysteine-rich amino acid sequence motif (LIM) with putative zinc-binding activity, and may be involved in regulating ordered cell growth. Other genes in the family include CSRP1 and CSRP3. Alternative splicing results in multiple transcript variants.

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