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Rabbit anti-Mus musculus (Mouse) Bag3 Polyclonal Antibody, HRP conjugated

The antibody against Bag3 was raised in rabbit using the Recombinant Mouse BAG family molecular chaperone regulator 3 protein (2-577AA) as the immunogen. This antibody exists as a hrp conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA.

ADC-49380A

The antibody against Bag3 was raised in rabbit using the Recombinant Mouse BAG family molecular chaperone regulator 3 protein (2-577AA) as the immunogen. This antibody exists as a hrp conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA.

$299.00

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Specifications


Cat.No ADC-49380A ClonalityPolyclonal
Host SpeciesRabbitTarget NameBAG3
Target SynonymsBag3 antibody; Bis antibody; MNCb-2243BAG family molecular chaperone regulator 3 antibody; BAG-3 antibody; Bcl-2-associated athanogene 3 antibody; Bcl-2-binding protein Bis antibodyFormLiquid
Species ReactivityMouseIsotypeIgG
Storage Buffer0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4Purification Method>95%, Protein G purified
ConjugateHRP conjugatedApplicationELISA
StorageUpon receipt

Immunogen Information


Immunogen DescriptionRecombinant Mouse BAG family molecular chaperone regulator 3 protein (2-577AA)Target SpeciesMus musculus (Mouse)
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDQ9JLV1
Background Information
  • Uniprot Id

    Q9JLV1

  • Target Species

    Mouse

  • Target Name

    BAG3

  • Target Full Name

    BAG family molecular chaperone regulator 3

  • Target Function

    Co-chaperone for HSP70 and HSC70 chaperone proteins. Acts as a nucleotide-exchange factor (NEF) promoting the release of ADP from the HSP70 and HSC70 proteins thereby triggering client/substrate protein release. Nucleotide release is mediated via its binding to the nucleotide-binding domain (NBD) of HSPA8/HSC70 where as the substrate release is mediated via its binding to the substrate-binding domain (SBD) of HSPA8/HSC70. Has anti-apoptotic activity. Plays a role in the HSF1 nucleocytoplasmic transport.

  • Target Subcellular Location

    Nucleus. Cytoplasm.

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