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Rabbit anti-Human GC Polyclonal Antibody

The antibody against GC was raised in rabbit using the Recombinant Human Vitamin D-binding protein (19-474AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IHC.

ADC-50668A

The antibody against GC was raised in rabbit using the Recombinant Human Vitamin D-binding protein (19-474AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IHC.

$299.00

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Specifications


Cat.No ADC-50668A ClonalityPolyclonal
Host SpeciesRabbitTarget NameGC
FormLiquidSpecies ReactivityHuman
IsotypeIgGStorage Buffer0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4
Purification Method>95%, Protein G purifiedConjugateNon-conjugated
ApplicationELISA, IHC, WBStorageUpon receipt

Immunogen Information


Immunogen DescriptionRecombinant Human Vitamin D-binding protein (19-474AA)Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDP02774
Background Information
  • Uniprot Id

    P02774

  • Target Species

    Human

  • Target Name

    GC

  • Target Full Name

    Vitamin D-binding protein

  • Target Function

    Involved in vitamin D transport and storage, scavenging of extracellular G-actin, enhancement of the chemotactic activity of C5 alpha for neutrophils in inflammation and macrophage activation.

  • Target Subcellular Location

    Secreted.

  • Target Protein Families

    ALB/AFP/VDB family

  • Target Tissue Specificity

    Expressed in the liver. Found in plasma, ascites, cerebrospinal fluid and urine.

  • Target Research Area

    Signal Transduction, Transport

  • Target Synonyms

    DBP; DBP/GC; GC; Gc globulin; Gc-globulin; GRD3; Group specific component; Group specific component vitamin D binding protein; Group-specific component; hDBP; VDB; VDBG; VDBP; Vitamin D binding alpha globulin; Vitamin D-binding protein; VTDB_HUMAN

  • Target Background

    The protein encoded by this gene belongs to the albumin gene family. It is a multifunctional protein found in plasma, ascitic fluid, cerebrospinal fluid and on the surface of many cell types. It binds to vitamin D and its plasma metabolites and transports them to target tissues. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

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