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The antibody against NDUFA2 was raised in rabbit using the Recombinant Human NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 protein (4-99AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.
The antibody against NDUFA2 was raised in rabbit using the Recombinant Human NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 protein (4-99AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.
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Immunohistochemistry of paraffin-embedded human kidney tissue using NDUFA2 Antibody at dilution of 1:100
| Cat.No | ADC-50807A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | NDUFA2 |
| Form | Liquid | Species Reactivity | Human |
| Isotype | IgG | Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 |
| Purification Method | >95%, Protein G purified | Conjugate | Non-conjugated |
| Application | ELISA, IHC | Storage | Upon receipt |
| Immunogen Description | Recombinant Human NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 protein (4-99AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | O43678 |
Uniprot Id
O43678
Target Species
Human
Target Name
NDUFA2
Target Full Name
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2
Target Function
Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
Target Subcellular Location
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Target Protein Families
Complex I NDUFA2 subunit family
Target Research Area
Transport
Target Synonyms
B8; CI B8; CI-B8; Complex I B8; Complex I-B8; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex 2 8kDa; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex 2; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2; NADH ubiquinone oxidoreductase B8 subunit; NADH-ubiquinone oxidoreductase B8 subunit; NDUA2_HUMAN; NDUFA 2; Ndufa2
Target Background
The encoded protein is a subunit of the hydrophobic protein fraction of the NADH:ubiquinone oxidoreductase (complex 1), the first enzyme complex in the electron transport chain located in the inner mitochondrial membrane, and may be involved in regulating complex I activity or its assembly via assistance in redox processes. Mutations in this gene are associated with Leigh syndrome, an early-onset progressive neurodegenerative disorder. Alternative splicing results in multiple transcript variants.
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