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The antibody against Havcr1 was raised in rabbit using the Recombinant Mouse Hepatitis A virus cellular receptor 1 homolog protein (22-237AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.
The antibody against Havcr1 was raised in rabbit using the Recombinant Mouse Hepatitis A virus cellular receptor 1 homolog protein (22-237AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.
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Immunohistochemistry of paraffin-embedded human kidney tissue using Havcr1 Antibody at dilution of 1:50
| Cat.No | ADC-51012A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | HAVCR1 |
| Form | Liquid | Species Reactivity | Mouse |
| Isotype | IgG | Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 |
| Purification Method | >95%, Protein G purified | Conjugate | Non-conjugated |
| Application | ELISA, IHC | Storage | Upon receipt |
| Immunogen Description | Recombinant Mouse Hepatitis A virus cellular receptor 1 homolog protein (22-237AA) | Target Species | Mus musculus (Mouse) |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q5QNS5 |
Uniprot Id
Q5QNS5
Target Species
Mouse
Target Name
HAVCR1
Target Full Name
Hepatitis A virus cellular receptor 1 homolog
Target Function
May play a role in T-helper cell development and the regulation of asthma and allergic diseases. Receptor for TIMD4. May play a role in kidney injury and repair.
Target Subcellular Location
Membrane; Single-pass type I membrane protein.
Target Protein Families
Immunoglobulin superfamily, TIM family
Target Tissue Specificity
Expressed by stimulated T-cells. Expressed during primary antigen stimulation.
Target Synonyms
Tim1; KIM-1; TIM-1; Timd1; TIM-1/KIM-1/HAVCR
Target Background
Enables phosphatidylserine binding activity. Acts upstream of or within positive regulation of mast cell activation; response to lipopolysaccharide; and response to wounding. Located in brush border and cell surface. Is expressed in brain; dorsal aorta; liver; lung; and reproductive system. Human ortholog(s) of this gene implicated in atopic dermatitis. Orthologous to human HAVCR1 (hepatitis A virus cellular receptor 1).
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