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The antibody against VPS53 was raised in rabbit using the Human VPS53 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB.
The antibody against VPS53 was raised in rabbit using the Human VPS53 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB.
$600.00
| Cat.No | ADC-51365A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | VPS53 |
| Form | Liquid | Species Reactivity | Human, Mouse, Rat |
| Isotype | IgG | Storage Buffer | 50% Glycerol, Avoid freeze / thaw cycles., PBS with 0.1% Sodium Azide |
| Purification Method | Antigen affinity purified | Conjugate | Non-conjugated |
| Application | ELISA, WB | Storage | Upon receipt |
| Immunogen Description | Human VPS53 | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q5VIR6? |
Uniprot Id
Q5VIR6
Target Species
Human
Target Name
VPS53
Target Full Name
Vacuolar protein sorting-associated protein 53 homolog
Target Function
Acts as component of the GARP complex that is involved in retrograde transport from early and late endosomes to the trans-Golgi network (TGN). The GARP complex is required for the maintenance of the cycling of mannose 6-phosphate receptors between the TGN and endosomes, this cycling is necessary for proper lysosomal sorting of acid hydrolases such as CTSD. Acts as component of the EARP complex that is involved in endocytic recycling. The EARP complex associates with Rab4-positive endosomes and promotes recycling of internalized transferrin receptor (TFRC) to the plasma membrane.
Target Involvement
Pontocerebellar hypoplasia 2E (PCH2E)
Target Subcellular Location
Golgi apparatus, trans-Golgi network membrane; Peripheral membrane protein. Endosome membrane; Peripheral membrane protein. Recycling endosome.
Target Protein Families
VPS53 family
Target Synonyms
FLJ10979; FLJ41112; FLJ61757; HCCS1; hVps53L; MGC39512; pp13624; Vacuolar protein sorting 53 (yeast); Vacuolar protein sorting 53; Vacuolar protein sorting 53 homolog (S. cerevisiae); Vacuolar protein sorting-associated protein 53 homolog; VPS53; VPS53_HUMAN
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