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The antibody against HPS6 was raised in rabbit using the Recombinant Human Hermansky-Pudlak syndrome 6 protein (221-319AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC, IF.
The antibody against HPS6 was raised in rabbit using the Recombinant Human Hermansky-Pudlak syndrome 6 protein (221-319AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC, IF.
$299.00
| Cat.No | ADC-06500A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | HPS6 |
| Form | Liquid | Species Reactivity | Human |
| Isotype | IgG | Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 |
| Purification Method | >95%, Protein G purified | Conjugate | Non-conjugated |
| Application | ELISA, IF, IHC | Storage | Upon receipt |
| Immunogen Description | Recombinant Human Hermansky-Pudlak syndrome 6 protein (221-319AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q86YV9 |
Uniprot Id
Q86YV9
Target Species
Human
Target Name
HPS6
Target Full Name
BLOC-2 complex member HPS6
Target Function
May regulate the synthesis and function of lysosomes and of highly specialized organelles, such as melanosomes and platelet dense granules. Acts as cargo adapter for the dynein-dynactin motor complex to mediate the transport of lysosomes from the cell periphery to the perinuclear region. Facilitates retrograde lysosomal trafficking by linking the motor complex to lysosomes, and perinuclear positioning of lysosomes is crucial for the delivery of endocytic cargos to lysosomes, for lysosome maturation and functioning.
Target Involvement
Hermansky-Pudlak syndrome 6 (HPS6)
Target Subcellular Location
Microsome membrane. Cytoplasm, cytosol. Early endosome membrane. Lysosome membrane.
Target Tissue Specificity
Ubiquitous.
Target Synonyms
BLOC2S3; FLJ22501; Hermansky Pudlak syndrome 6 protein; Hermansky-Pudlak syndrome 6 protein; HPS6; HPS6 biogenesis of lysosomal organelles complex 2 subunit 3; HPS6_HUMAN; MGC20522; Ru; Ruby eye protein homolog; Ruby-eye protein homolog
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