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The antibody against KLHL41 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human KLHL41 (NP_006054.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against KLHL41 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human KLHL41 (NP_006054.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-05098A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | KLHL41 |
| Target Synonyms | Krp1; KBTBD10; SARCOSIN; KLHL41 | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.01% thimerosal, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | Mouse heart, A-549, Mouse skeletal muscle, Rat skeletal muscle | Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human KLHL41 (NP_006054.2). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | O60662 | Immunogen Sequence |
Uniprot Id
O60662
Target Species
Human
Target Name
KLHL41
Target Full Name
Kelch-like protein 41
Target Function
Involved in skeletal muscle development and differentiation. Regulates proliferation and differentiation of myoblasts and plays a role in myofibril assembly by promoting lateral fusion of adjacent thin fibrils into mature, wide myofibrils. Required for pseudopod elongation in transformed cells.
Target Involvement
Nemaline myopathy 9 (NEM9)
Target Subcellular Location
Cytoplasm. Cytoplasm, cytoskeleton. Cell projection, pseudopodium. Cell projection, ruffle. Cytoplasm, myofibril, sarcomere, M line. Sarcoplasmic reticulum membrane. Endoplasmic reticulum membrane.
Target Tissue Specificity
Sarcomeric muscle.
Target Synonyms
cb52 ; fb24f05; fc15e07; Gm112; KBTBA_HUMAN; Kbtbd10; Kel like protein 23; Kel-like protein 23; Kelch related protein 1; Kelch repeat and BTB domain-containing protein 10; Kelch-related protein 1; KRP1; MGC143407 ; Sarcosin; sbcb52; wufb24f05; wufc15e07
Target Background
This gene is a member of the kelch-like family. The encoded protein contains a BACK domain, a BTB/POZ domain, and 5 Kelch repeats. This protein is thought to function in skeletal muscle development and maintenance. Mutations in this gene have been associated with nemaline myopathy (NM), a rare congenital muscle disorder.
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